Take No Prisoners 

For players who have a lot of experience, working against the inferior player is not as easy as it sounds. Players who compete in tournaments - even on a local level - on a regular basis have been heard to complain that to step way down in competition messes with their "rhythm." If a scenario usually results in a certain countermove that might be logical, even expected, from an experienced player, having someone in the pot with you who's not so experienced will bring about unorthodox plays that affect what your initial decisions are going to be, one way or another.

After all, for a player who is used to maneuvering with others on a mental and psychological level, it's kind of tough to get into a battle of wits with someone who is not truly engaged. Inexperienced players often don't know enough to be intimidated by better players. They might make calls that are completely unanticipated. If you've got a few players at the table who are inexperienced and therefore a little "looser" than the average player, they may be producing situations where there are more players you have to beat out to win certain pots, while wiser players know to fold.

Over the long run, of course, the better players should be able to win over the novices on a consistent basis. But it takes adjustment. Some people have a tendency to act too smart; even worse is to be "three smart," as one poker player once said. Don't think yourself to death. One option might be to think more about a "vanilla" game, focusing on good fundamentals. Going back to the boxing analogy, when the opponent is going from all angles, throwing haymakers, it's probably best not to engage in that kind of slugging match with him, but rather to stand back, wait for the clear mistake, and pounce.

At holdem betting poker, it's much the same thing. Find the weakness, be patient, exploit it - and take no prisoners.